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Chronic stress is the problem

3.3 Treatment strategies Calcium channel blockers, such as amlodipine, have shown promise in preventing cocaine-induced vascular toxicity by lowering blood pressure and reducing headache frequency ( 4 Synthetic cathinones Synthetic cathinones, colloquially known as bath salts, exhibit profound neurotoxic effects by affecting monoaminergic neurotransmission, oxidative stress, excitotoxicity, and neuroinflammation

Unfortunately, NAC is not readily available from the diet and it cannot be readily produced by the body, so supplementation is a straightforward way of promoting its protective benefits

Structure-activity relationship studies of curcumin analogues