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They are unavoidable in these modern times both in our polluted cities and our poorly engineered food supplies

Eur J Pharmacol 158:6167, 1988 Sikiric P, Rotkvic I, Mise S, Petek M, Rucman R, Seiwerth S, Zjacic Rotkvic V, Duvnjak M, Jagic V, Suchanek E, Grabarevic Z, Anic T, Brkic T, Djermanovic Z, Dodig M, Marovic A, Hernandez DE: Dopamine agonists prevent duodenal ulcer relapse: A comparative study with famotidine and cimetidine

Yes, actually - they're made to work as a set

The biologically active form of vitamin B6, pyridoxal 5-phosphate (P5P), is used as a cofactor in hundreds of different cellular reactions.[ref] Let me hit the highlights here: Nervous system and neurotransmitters : P5P is essential in the process of synthesizing serotonin from the amino acid tryptophan