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These effects are mediated through downstream activation of transcription factors such as c-Fos, c-Jun, and EGR-1, which regulate genes involved in cell cycle progression, extracellular matrix remodeling, and angiogenic signaling [26]

General anesthesia is often necessary for various medical procedures, but as with all medications, the drugs used for general anesthesia can have unwanted effects on the body

In the context of nephrology, nephroprotection concerns the plan, both implementation and withdrawal, of drugs and procedures leading to the protection of healthy kidneys and alleviation of symptoms in diseased kidneys