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On the other hand, other authors have shown that MPP + induces negative effects in astrocytes, such as loss of viability, impairment of energetic metabolism of mitochondria, ROS generation and decrease in the glutamate clearance by astrocytes [81,85,86]

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People with Down syndrome have a relatively low methylation functional status compared to people without Down syndrome

The new bioavailability would be F = 30% (1 - 0.7)