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The safety profile was statistically indistinguishable from placebo across all trials
Biochemical tests in these patients may reveal decreased serum copper and ceruloplasmin levels (Table 2)
A method of reversing, ameliorating or slowing progression of at least one symptom of Lewy body pathology in a patient in need thereof, comprising the step of administering to said patient an amount of one or more hepatocyte growth factor mimics sufficient to reverse, ameliorate or slow progression of said at least one symptom, said one or more hepatocyte growth factor mimics having a general structural formula 1 2 3 wherein Ri is one of an N-acyl group, a substituted or unsubstituted phenyl, a norleucine group, and an amino acid selected from tyrosine, phenylalanine, aspartic acid, arginine, isoleucine, serine, histidine, glycine, cysteine, methionine, tryptophan, lysine norvaline, ornithine, and s-benzyl cysteine
[3] Another review of 14 randomized controlled trials also did not consistent evidence of benefit with the use of vitamin B12 supplements, alone or with other B vitamin supplements, on cognitive function in people with either normal or impaired cognition
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