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Methods Sample preparation for ice nucleation experiments Aqueous solutions were prepared at concentrations of 5 mg mL 1 , 0.5 mg mL 1 , and 5 10 4 mg mL 1 using ultrapure water (HPLC water, Sigma-Aldrich) and commercially available compounds, which were obtained from Sigma-Aldrich unless otherwise noted

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is essential for mitochondrial energy production, DNA repair, and numerous enzymatic reactions, researchers have investigated how modulation of NNMT activity may influence cellular bioenergetics and metabolic efficiency