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PE-22-28 inhibits TREK-1 with an IC50 of 0.12 nM, as determined by electrophysiology in HEK293 cells expressing human TREK-1

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Preferred subcutaneous sites include the abdomen and the outer upper arms, providing straightforward access for individuals administering their own injections: Abdomen: Injections are given at least two inches away from the navel, allowing for a broad area of fat tissue

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