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However, when your body has more histamine than it can efficiently break down, it can lead to symptoms like:( 1 ) Skin problems like itching, rashes, and eczema Irregular and/or painful periods Allergic asthma and difficulty breathing Motion sickness (boat, car, amusement park) Runny nose, sneezing, nosebleeds, or red face Bloating, excessive gas, abdominal cramping, or nausea Food intolerances and sensitivities Dizziness Feelings of unease Headaches or migraines Difficulty falling asleep Pregnancy complications Acid reflux, stomach and digestive problems Heart palpitations The Two Main Histamine Genes Genes make enzymes

doi: 10.1002/hep.32062 46 WangWGreenMChoiJEGijonMKennedyPDJohnsonJKet al

DSIP may more broadly influence deep sleep architecture and stress response Benzodiazepines carry significant risks of dependency and cognitive side effects

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