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3d, e, Supplementary Fig

& Miskowiak, K

GSH is synthesized de novo in the brain by astrocytes and research has demonstrated increased GSH synthesis during oxidative stress-related toxicity in vitro , proposing in vivo synthesis of this antioxidant might be sufficient to not detect significant changes (14)

There also is a question of whether ketamine administration should be reserved for inpatient use or can be considered for outpatient treatment with dosing via tinctures, sublingual tablets, lozenges, or nasal sprays