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Tetrandrine inhibits migration and invasion of rheumatoid arthritis fibroblast-like synoviocytes through down-regulating the expressions of Rac1, Cdc42, and RhoA GTPases and activation of the PI3K/Akt and JNK signaling pathways

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The delivery of a sufficient amount of oxygen to the hypoxic site without leaking any oxygen into blood circulation had proven difficult, but hydrogels offered one route that the exogenous oxygen could be delivered in a suitable dose, directly to the target site, and activated to trigger the release of oxygen, reducing the aforementioned issues previously encountered

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