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Moreover, a relatively small sample size of the subgroup of patients with severe vasculogenic ED might have prevented to capture slightly significant improvements in PSV at dynamic PDU upon l-ARG supplementation, particularly in patients with borderline scores indicating severity, therefore making it challenging to provide conclusive information concerning the potential effect of l-ARG supplementation in patients with borderline severe vasculogenic ED

P = 2.2 10 56 , effect = 0.10 s.d.) (Supplementary Table 4)

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Therefore, patients must always wear a broad-spectrum sunscreen that guards against both UVA and UVB rays, which can stimulate melanocytes to produce melanin