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(2001) investigated AOD9604 in obese Zucker rats and observed that chronic administration was associated with reduced body weight gain without changes in IGF-1 levels or glucose tolerance, distinguishing its activity profile from that of full-length growth hormone [1]

Pharmacokinetic profiles for the compound place its plasma half-life in the neighborhood of 45 minutes after parenteral administration in animal models, which informs typical dosing intervals in published experiments

Handle using appropriate laboratory safety procedures

However, COX-2 inhibitors carry their own cardiovascular risks and should only be prescribed under specialist guidance, with a concurrent PPI, and following individual risk assessment (BNF