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This pro-angiogenic activity, mediated at least in part through upregulation of VEGF receptor expression, is considered a key contributor to the accelerated tissue repair seen across different injury models

Along the same lines as ivacaftor and hypertonic saline, several pharmaceutical groups have been pursuing pharmaceuticals that target other ion channels to improve mucociliary clearance in a cftr -independent manner

FDA approves zidesamtinib for ROS1-positive NSCLC after prior TKIs, offering a new option for resistant and CNS-active disease

Linus Pauling Institute Oregon State University Updated in January 2014 by: Barbara Delage, Ph.D