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In addition, high levels of most of these OS biomarkers [95,96,97,98], together with high levels of ascorbate free radical [96], and two products of NO oxidation, such as nitrite and nitrate [99], were also detected in cerebrospinal fluid (CSF) samples from ALS patients, showing a positive correlation with 8-OHdG level and disease severity over the 9-month duration of the prospective study [95]

BPC-157 (15 aminozuren, ~1.419 Da) moduleert het stikstofoxide-systeem, prostaglandinen en groeifactorsignalering, met bijzondere relevantie voor pees-, ligament- en GI-weefsel

It is normally present in small amounts in urine

These systems enhance the efficiency of delivery, help cross the physical barrier of the lung, and exhibit greater antimicrobial activity compared to the drug that has not been modified (Solanki et al., 2024)