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Plant polyphenols such as quercetin exhibit strong antioxidative and anti-inflammatory activity by scavenging radicals, chelating metals, and activating the Nrf2ARE pathway, thereby upregulating antioxidant enzymes like SOD, catalase (CAT), and glutathione peroxidase (GPx)

Accordingly, the Zetpil Melatonin Suppository is the only therapeutic melatonin option currently available

developed a copper-based metal-organic framework (MOF) nanozyme with dual peroxidase- and oxidase-like activities that exerts potent metabolic intervention in CRC [101]

Echinatin mitigates sevoflurane-induced hippocampal neurotoxicity and cognitive deficits through mitigation of iron overload and oxidative stress