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Similar is the case with enzymes responsible for Phase II metabolism, which also produce detrimental effects on the efficacy of chemotherapeutic agents, owing to overexpression of the enzymes due to prior exposure to the same agents

Erucamide targets CD11b + myeloid cells To evaluate the effects of erucamide on healthy ocular tissue and to determine the cellular and biological target of erucamide, it was intravitreally administered into 1-month-old wild-type (WT) C57BL/6J mouse retinas