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The overall pattern and frequency of adverse events during the longer-term premarketing trials was similar to those described in Table 1, though several of the most common events were reported by a greater proportion of patients with long-term use (e.g., nausea was reported in 40% of patients treated with CHANTIX 1 mg twice daily in a one year study, compared to 8% of placebo-treated patients)

In addition to aesthetics, smoking increases plaque buildup and bacteria inside your mouth, potentially raising your risk of tooth decay or gum disease

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women were smoking at a much higher rate than women in most European countries, particularly those in Southern Europe, and it is the smoking behavior during that period that affected life expectancy in the 1980s and 1990s