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Description

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Packer M et al., SUMMIT, NEJM 2024 (NEJMoa2410027, PMID 39555826) : tirzepatide and HFpEF with obesity, HR 0,62 composite endpoint

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In the presence of endotoxin, the cascade cleaves the substrate, releasing a colored molecule (a chromophore)

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Pre-Existing Inflammation or Underlying Conditions If the injection site was already significantly inflamed before PRP, the additional inflammatory response triggered by the injection may intensify pain

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