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This product is intended strictly for laboratory research purposes and is not for human or animal consumption, medical use, or diagnostic use

Tumor necrosis factor- induces ADAMTS-4 expression in human osteoarthritis chondrocytes

It activates both the extrinsic apoptotic pathway through caspase-8 and the intrinsic pathway through caspase-9, ultimately resulting in cleavage of executioner caspase-3

IGF-1 LR3 (Long R3 IGF-1, CAS 946870-92-4) is a recombinant 83-amino-acid analogue of insulin-like growth factor 1 with an N-terminal extension and Arg3 substitution, extending plasma half-life and reducing IGFBP binding