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A meta-analysis of 41 studies from 36 perinatal cohortsincluding populations from the United States, the Netherlands, the United Kingdom, Denmark, Finland, Sweden, Australia, and Norwayreported that children of women with pregestational overweight had a 17% higher likelihood of neurodevelopmental disorders, while those of women with obesity showed a 51% increased risk compared to children of mothers with normal weight (171)

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M.GarssenJ.Van BergenhenegouwenJ.OverbeekS

The expression of SPARC is minimal in most normal adult tissues but is increased after injury