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doi: 10.1007/s00415-012-6513-7 283 LiX-LZhangZ-CZhangBJiangHYuC-MZhangW-Jet al

In Mecp2-deficient mice, NTS neurons show significantly reduced amplitudes and frequencies of sIPSCs and mIPSCs, indicating impaired synaptic transmission, and decreased eIPSC amplitudes, though the paired-pulse ratio (PPR) remains unchanged, suggesting that postsynaptic mechanisms may contribute to the weakening of GABAergic inhibition