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doi: 10.3389/fnut.2024.1463502 287

Figure 1 shows the effect of oxidative stress and the interaction of aging and age-related diseases

This, in turn, leads to reduced brain tryptophan concentration, decreased 5-HT levels, and diminished 5-HT receptor binding, which may underlie the 5-HT system dysfunction, impaired neurotransmission, and negative cognitive effects observed in SZ