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So the chemically castrated patient, meaning they have no testosterone so if you treat a patient who has no testosterone and you take them from zero testosterone to normal testosterone, so to take them from, let's say, zero to 350, um, during that climb from zero to 350, you can increase theoretically, the risk of exasperating a prostate cancer that's pre pre-existing was the fear

Jan 8: Astellas has failed to gain approval for what would be the first approved therapy targeting claudin 18.2 (CLDN18.2), a transmembrane protein expressed on the surface of gastric epithelial cancer cells