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Such approaches could enable the fine-tuned correction of organelle-specific zinc flux without broadly altering total cellular zinc levels

In addition to the TLR7 agonist-loaded nanoparticles that can polarize M2 TAMs to M1 TAMs, liposomal R848-LPs loaded with the TLR-7/8 agonist resiquimod (R848) can also rapidly accumulate at tumor sites and R848-targeting TAMs can polarize TAMs to type M1, and this nanoparticle can also enhance the anti-tumor effect of therapeutic antibodies by enhancing antibody-dependent cell phagocytosis (ADCP) effects (40)

Anderson Cancer Center, Houston, TX, 2002 - 2005 Assistant Professor, Thoracic and Cardiovascular Surgery, The University of Texas M

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