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These peptides primarily act through the GH/IGF-1 axis, which activates the PI3K/Akt/mTOR cascadestimulating satellite cell proliferation, muscle protein synthesis, and chondrocyte matrix production

We outline major translational and biological challenges, identify key gaps for future research and discuss emerging approaches aimed at achieving durable and scalable obesity treatment

Mechanism of Action Indication Fountain of Youth: Anti-Aging: Promotes DNA repair, reduces oxidative stress, and enhances cellular health

In the CNS, HGF/c-Met signaling governs: Neuronal Survival: Protecting neurons from apoptosis (programmed cell death) during metabolic stress or excitotoxic injury