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It also supports molecules like decorin, dermatan sulfate, and chondroitin sulfate, all of which help keep skin hydrated and cushioned from the inside. Newer GHK-Cu Research on Skin Repair In 2023, a study in the Journal of Cosmetic Dermatology tested GHK-Cu alongside hyaluronic acid and found that the two together boosted collagen production more than either could alone. A 2024 review in Applied Sciences highlighted how the peptide supports wound healing, helps new blood vessels form, and brings the right repair cells (macrophages, monocytes, and mast cells) to areas that need healing. A 2025 review published in International Journal of Medical Sciences went even further, looking at next-generation GHK-Cu formulations

Increased heart rate or palpitations , especially in sensitive individuals

[DOI] [PMC free article] [PubMed] [Google Scholar] 31.Hameed M.Q., Hodgson N., Lee H.H., Pascual-Leone A., MacMullin P.C., Jannati A., Dhamne S.C., Hensch T.K., Rotenberg A

Gordon also underscores the importance of hydration and water quality