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The ability of these chemicals to induce ferroptosis will also be discussed with special attention paid to their effects in SH-SY5Y human neuroblastoma cells since these cells possess properties of dopaminergic neurons, and, therefore, have a long history of use as an in vitro model in studies on PD (Cheung et al., in vitro model of chemically-induced PD showed that apoptosis is the main mode of cell death induced by PQ (Klintworth et al., 2007
Additionally, C-incubation time (min) demonstrates a moderate effect with a p-value of 0.0284
Individual responses to the treatment may vary
Another trial is testing whether N-acetylcysteine affects inflammatory and oxidative stress biomarkers in patients with tobacco use disorders and bipolar disorder (39)
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