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Existing research has confirmed significant correlations between sputum NSP activity levels and patient clinical outcomes, laying theoretical foundations for their use as predictive markers ( Exploration of combination treatment strategies deserves investigation

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Hence, it is also possible to assess the occurrence of an in vivo DILI episode by monitoring liver biomarkers in other biological fluids such as serum or urine, obtained by non-invasive or minimally invasive procedures, avoiding the need for liver biopsies for diagnostic purposes