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Some rodent studies used oral gavage with reported effects, supporting the plausibility of systemic activity via the oral route

10.1016/j.pscychresns.2017.10.001 Psychiatry Res Neuroimaging

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Thirteen of the patients met criteria for residual schizophrenia (see SA6 for details of exclusions and a discussion relating to our sample size, clinical and demographic features of the sample are reported in ST4)