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ACTL6A is co-amplified with p63 in squamous cell carcinoma to drive YAP activation, regenerative proliferation, and poor prognosis

Strong oxidants such as hydrogen peroxide (H 2 O 2 ) instead readily modify protein thiols beyond reversible redox states, to form sulfinic (-SO 2 H) and sulfonic acids (-SO 3 H), thus preventing conversion into the disulfide-linked pathological species dsNNTTR