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NAD + can inhibit the release of presynaptic glutamate, reduce the induced excitatory postsynaptic current, and weaken excitatory neurotransmission, thereby inhibiting bilirubin-induced hyperexcitability of ventral cochlear nucleus neurons [124]

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This method is less precise because it does not deposit the medication near the target nerve root, and the steroid solution is free to spread within the epidural space

in fact, it is the most common GST expressed outside the liver