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Finerenone, a novel selective mineralocorticoid receptor antagonist (MRA), has manifested both cardiovascular and kidney protection confirmed by two phase III trials, Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease (FIDELIO-DKD) (145) and Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease (FIGARO-DKD) (146) together with FIDELITY pooled analysis (147)

Though the use of glutathione is mostly safe, individuals should be careful of some groups

This article aims to provide a comprehensive overview of the role of Gln transporters in DSMTs, along with an exploration of targeted therapeutic drugs, with the goal of providing valuable insights into the drug discovery process for DSMTs therapy and deepening our understanding of the underlying mechanisms