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Previously, two studies have required smokers to use plain packs of cigarettes in a real-world setting, although these studies relied on self-report of smoking behavior and did not ask participants to report the number of cigarettes smoked [2, 3]

A comprehensive search of Web of Science, Embase, and PubMed was conducted to identify observational studies that assessed the association between e-cigarette use and the risk of COPD, providing risk estimates (hazard ratios, risk ratios, or odds ratios) for current, former, and ever e-cigarette users

While lung damage from smoking can be significant, some effects can improve after quitting

These other products are right there. A number of prominent groups, including the American Academy of Pediatrics, the American Lung Association and the American Heart Association have expressed similar concerns