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This finding suggests that these genes may play a role in modulating the neutrophil response under hypoxic conditions, thus involved in the pathogenesis of AS

Identification of new inhibitors for human hematopoietic prostaglandin D2 synthase among FDA-approved drugs and other compounds

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When we speak about the damaging effects of oxygen we are not referring to O2 but to the various reactive oxygen species (ROS), the superoxide anion (O2-), the hydroxyl radical (OH.), singlet oxygen (1O2), and hydrogen peroxide (H2O2)