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chronic, maintenance of weight balance Synergy with leptin , amylin restores leptin sensitivity in obese models Synergy with CCK and GLP-1 , multi-pulse pathways of appetite suppression No tolerance , chronic administration of amylin preserves efficacy Why it matters: Lutzs review article established the scientific basis for amylin pharmacotherapy of obesity

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These drugs are commonly implicated in drug pseudoallergies (these are allergic-type reactions that do not involve the immune system) Foods such as salicyclates, azo dye, food colorings (for example, tartrazine [102]), preservatives (such as benzoates [210-220]), and other food additives Tight clothing Viral infections

DOI: 10.1182/blood-2002-08-2548 73