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290 A may increase cytosolic calcium levels and impair mitochondrial calcium buffering functions through various pathways including plasma membrane receptors and calcium channels, 291 enhanced ER calcium release, 292 and the mitochondrial inner membrane calcium channel MCU

Nat Med (2018) 24(7):103646

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As illustrated in Figure 8B, the anti-NeuN antibody was used to label the nucleus of SGN and the fluorescence of NF-B p65 was mainly detected in the cytoplasm of SGNs in control group (Figure 8B)