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10.1007/s10522-015-9578-8 Biogerontology

What the evidence does not support is the idea that the combination itself has been tested

We also allow the inputs to vary as functions of time (for example the amino acid input will vary because of meals) and compute the time course of each concentration and reaction rate

Glucocorticoid-induced osteoporosis: both in vivo and in vitro concentrations of glucocorticoids higher than physiological levels attenuate osteoblast differentiation