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Consequently, active individuals and those who spend significant time outdoors have higher ongoing vitamin C requirements

Initially conceptualized as a therapeutic for neurodegenerative disorders such as Alzheimers and Parkinsons disease, its primary mechanism of action involves high-affinity binding to hepatocyte growth factor (HGF) and its cognate receptor c-Met

Studies such as this one published in PMC highlight the role of malabsorption from mucocutaneous disorders like epidermolysis bullosa can lead to deficiencies that cannot be addressed adequately with oral supplements

As an example, we used the common chemotherapeutic drug Doxorubicin, which can indeed induce senescence (Cahu et al., 2012