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58 Earlier studies found that iron overload in mice increases oxidative stress in bone, leading to changes in bone microstructure and mineral deposition properties, resulting in osteoporosis

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8 Avoiding Acetaminophen/NSAID Toxicity The most effective approach to minimizing acetaminophen and NSAID toxicity would be avoiding their usage altogether and choosing alternative means for treatment of inflammation and pain (For more information, see Life Extensions Chronic Inflammation and Chronic Pain protocols)