So I always say that, okay, I'm not saying not to drink alcohol, but I'm saying that, hey, if you're in a habit of drinking alcohol, then make sure everything surrounding that, optimize your glutathione levels by eating the right fruits, you know, reducing everything else in terms of exposure, take supplementations, whatever
Mice with inactivating mutations in the gene coding for the enzyme alcohol dehydrogenase 5 (Adh5) and in the gene coding for the factor Fanconi Anaemia Complementation Group D2 (Fancd2) accumulate FA-DNA adducts and present hematopoietic stem cell attrition, which correlates with genome instability in the hematopoietic compartment 9
doi: 10.3390/antiox9050365
In mammals, PMEL fibrils have emerged as the first human functional amyloid described in the literature (Fowler et al., 2006)