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Int J Dermatol 1999;38:54650

This mitochondrial fraction is functionally critical, as demonstrated by the restoration of ferroptosis sensitivity in CHAC1-null cells through expression of a mitochondrially targeted CHAC1 (Ward et al., 2024)

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While promoting angiogenesis and decreasing inflammation through a number of mechanisms, it supports cell migration, differentiation, and cytoskeletal remodeling