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PubMed 18068698 TB-4 / TB-500 product mislabeling documented bidirectional mislabeling between full-length TB-4 (43 aa) and the TB-500 fragment (residues 1723) in marketed peptide products: Esposito M et al

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TB-500 / T4 also rests mostly on decades of preclinical work, but the T4 compound class has reached human clinical study in at least one delivery context: a topical T4 ophthalmic candidate (RGN-259) was evaluated in human Phase 2 trials for corneal/dry-eye endpoints (Crockford et al., Ann N Y Acad Sci 2010)

These findings collectively point to Epitalon as a functional telomerase modulator, capable of extending telomeres, delaying replicative senescence, and maintaining cellular health across multiple biological systems