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Using the nude mice model with subcutaneous xenograft, a study found that 80% more zinc was detected in the tumors implanted with ZIP4 stably overexpressed MIA-ZIP4 cells compared with the normal group

Nanomaterials, such as mesoporous zinc oxide, are being explored for topical applications, while smart nano-delivery systems targeting the fungal microenvironment represent a promising frontier (Bayat et al., 2022

NAC has been associated with rare serious reactions such as hypersensitivity and bronchospasm as well as common less severe reactions such as nausea and vomiting, malodorous stool and mild allergic reaction 9