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Efficacy of local polymer-based and systemic delivery of the anti-glutamatergic agents riluzole and memantine in rat glioma models

Studies find GhK-cu can tame inflammation, promote vascular health, and regulate hormone pathways in reproductive tissues

Moreover, the debate between localized, stable glutamine levels, and circulating levels within the tumor and the surrounding cells is of significant concern and needs thorough dissection and mechanistic understanding (Figure 2)