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Investigating how immune cells and their secreted factors influence the pathogenesis of osteoporosis through the regulation of bone metabolism and the inflammatory microenvironment is essential for understanding disease progression and developing novel therapeutic strategies

Obtaining injections outside regulated NHS settings may involve inappropriate dosing, lack of monitoring, non-sterile technique, and unnecessary financial cost without clinical benefit

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A material that does not influence cell mortality may still elicit sub-lethal effects on the genome and epigenome, particularly at low doses