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Pexidartinib (PLX-3397) induces cell apoptosis and has anti-tumor activity
rheumatoid arthritis
Venetoclax induces autophagy
Stimulates insulin and suppresses glucagon secretion in a glucose-dependent manner
DAPT Pack Size:10 mM * 1 mL in DMSO Pexidartinib (PLX-3397) induces cell apoptosisDAPT (GSI IX) is a potent and orally active secretase inhibitor with IC50s of 115 nM and 200 nM for total amyloid (A) and A42, respectively. DAPT inhibits the activation of Notch 1 signaling and induces cell differentiation. DAPT also induces autophagy and apoptosis. DAPT has neuroprotection activity and has the potential for autoimmune and lymphoproliferative diseases, degenerative disease and cancers treatment.
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