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Comparing CBD to THC, our analyses on the DEGs and enriched pathways across datasets indicate that CBD has a more consistent gene regulatory signature than THC across datasets, and the genes and pathways also agree with CBDs well-characterized antioxidant, anti-inflammatory, and neuroprotective effects (Al-Khazaleh et al

occasional use , especially in ritual or meditative settings, and avoid daily consumption to reduce tolerance , nasal irritation and the risk of nicotine dependence