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Concurrently, a clinical study involving 98 pSS patients and 105 healthy controls (208) found that butyrate-producing bacteria were significantly reduced in pSS patients, and this reduction correlated negatively with increased Th17 cells and an imbalance in Th17/Treg

Additionally, the doses and exposure paradigms used in the animal studies to identify hazards associated with jet fuel exposure may not be relevant to expected human exposure scenarios, limiting the ability to draw conclusions about effects in humans where only data in animals are available

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IGF-IR signaling attenuates the age-related decline of diastolic cardiac function