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Coffin et al., in vivo , demonstrating that otoprotective drug discovery in zebrafish translates to mammalian systems (Owens et al., 2008

In addition to providing colonic epithelial cells with an energy substrate to sustain barrier function, butyrate also promotes Treg cell development via HDAC inhibitionmediated histone H3K27 acetylation at the Foxp3 gene locus (193195)

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After all, can we really say a skin-care product is the "best" for people over 50 if the only testers we've solicited opinions from folks who have yet to hit 30