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4 Probiotics and prebiotics as adjunctive therapeutic strategies in hypothyroidism The recognition of the gut-thyroid axis as a pivotal regulator of endocrine and immune homeostasis has spurred increasing interest in microbiota-targeted interventions for hypothyroidism

Based on these data, it is understood that metformins ability to treat type 2 diabetes may be linked to its impact on the gut microbiota and its generation of short-chain fatty acids (SCFAs)